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Orthomolecular Methyl B Complex–60 capsules

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Rejuvenescence cream has helped lessen the itch and flaky condition of my skin especially my legs. Although I find that it needs to be reapplied about 3hrs later. I like the way it absorbs quickly and leaves no sticky or greasy residue. There is no scent which is a blessing. I will be purchasing this product in the future.
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Great customer service!!!
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Mike K

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I received my order in record time. Amazon could not have beaten the price and timing. Thank you for excellent customer service.
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Linda S

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Great job as always
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Alice L

TARGET GB-X

TGBX
$45.00
In stock
1
Product Details
Clover Product ID: BXMK32W0EAA3E
UPC: 790616310081
Brand: Klaire Labs
Unit Count: 1
Unit Count Type: Sachet
Key Product Features 1: Supports positive mood
Key Product Features 2: Blend of 9 probiotic strains
Key Product Features 3: Designed to influence the gut-brain axis
Key Product Features 4: Clinically shown to decrease overall cognitive reactivity to sad mood, rumination, negative thoughts, and aggressive thoughts.
Key Product Features 5: Hypoallergenic, non-GMO powder in single-serving sachets
Serving Recommendation: 1 Sachet (Approx. 2 g)
Product Benefit: Clinically demonstrated mood support
Item Form: Powder
Allergen Information: Maize starch
Condition: New
Package Quantity: 1
Number of Items: 30
Product Expiration Type: On package
: 2 gm
: 1.50

A targeted probiotic blend clinically demonstrated to support mood†

30 SACHETS

Caution

Do not exceed the recommended daily serving. When antibiotics are used, wait 2-3 hours before using this product. If you are pregnant, nursing, have a medical condition, or taking prescription drugs, consult your healthcare professional before using this product. Keep out of reach of children.


Serving Size 1 Sachet (Approx. 2 g)
Amount Per Sachet % Daily Value
Calories 5
Total Carbohydrate 2 g <1%**
Sodium 70 mg 3%
Potassium (as potassium chloride) 35 mg <1%
Ecologic BARRIER Probiotic Blend (5 billion CFU) 2 g
Lactobacillus casei W56 *
Lactobacillus acidophilus W37 *
Lactobacillus brevis W63 *
Lactococcus lactis ssp. lactis W58 *
Bifidobacterium animalis ssp. lactis W52 *
Lactococcus lactis ssp. lactis W19 *
Lactobacillus salivarius W24 *
Bifidobacterium bifidum W23 *
Bifidobacterium lactis W51 *
* Daily value not established
** Percent Daily Values are based on a 2,000 calorie diet.

Other Ingredients:

Maize starch, maltodextrin, inulin, polydextrose, vegetable protein, magnesium sulfate, and manganese sulfate.

Target gb-X is a probiotic supplement specifically designed to support positive mood by influencing the gut-brain axis through the microbiome. It is powered by Ecologic BARRIER, a 5B CFU blend of 9 probiotic strains, that has been clinically shown to decrease overall cognitive reactivity to sad mood, rumination, negative thoughts, and aggressive thoughts.1 Heightened cognitive reactivity to sad mood is an established risk factor for more serious mood alterations in otherwise healthy individuals, and is therefore considered an important target for interventions.

  • Powered by Ecologic BARRIER, a 5B CFU blend of 9 probiotic strains
  • Protected by PROBIOACT® Technology for optimal efficacy and shelf-stability
  • Hypoallergenic, non-GMO powder in single-serving sachets

Target gb-X Mechanism

Target gb-X with Ecologic BARRIER was specifically designed to influence the gut-brain axis through defined mechanisms including strengthening of the gut barrier function, modulation of cytokines and inflammatory response, production of potentially neuroprotective metabolites, and HPA regulation. Preclinical research emphasized a pronounced shift away from macrophage-produced cytokines to T-lymphocyte-produced cytokines, a reduction in circulating lipopolysaccharide endotoxins, and a marked reduction in transcription of hippocampal genes related to HPA regulation.2

Probiotics and the Gut-Brain Axis

The gut-brain axis refers to the bidirectional communication network between the central and autonomic nervous systems and the intestines. Gut-brain communications are mediated by the immune system, endocrine connections such as the hypothalamic-pituitary-adrenal (HPA) axis, and neural pathways involving the enteric nervous system. The gut microbiota is now known to play a pivotal role in gut-brain communications. It is a complex interaction whereas the microbiota engages locally with intestinal cells as well as communicating directly with the central nervous system through neuroendocrine, immune, and metabolic pathways.3 Research into gut-brain mechanisms is rapidly expanding our understanding and serves to inform the development of targeted probiotic formulations.


References:

  1. Steenbergen L, Sellaro R, van Hemert S, Bosch JA, Colzato LS. A randomized, controlled trial to test the effect of multispecies probiotics on cognitive reactivity to sad mood. Brain Behav Immun. 2015 Aug;48:258-64.
  2. Abildgaard A, Elfving B, Hokland M, Wegener G, Lund S. Probiotic treatment reduces depressive-like behaviour in rats independently of diet. Psychoneuroendocrinology. 2017 May;79:40-48.
  3. Carabotti M, Scirocco A, Maselli MA, Severi C. The gut-brain axis: interactions between enteric microbiota, central and enteric nervous systems. Ann Gastroenterol. 2015 Apr-Jun; 28(2): 203–209.
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